Nonalcoholic Fatty Liver Disease Cirrhosis: A Review of Its Epidemiology, Risk Factors, Clinical Presentation, Diagnosis, Management, and Prognosis

Can J Gastroenterol Hepatol. 2018 Jul 2:2018:2784537. doi: 10.1155/2018/2784537. eCollection 2018.

Abstract

Cirrhosis is the common end stage of a number of chronic liver conditions and a significant cause of morbidity and mortality. With the growing epidemic of obesity and metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease worldwide and will become one of the leading causes of cirrhosis. Increased awareness and understanding of NAFLD cirrhosis are essential. To date, there has been no published systematic review on NAFLD cirrhosis. Thus, this article reviews recent studies on the epidemiology, risk factors, clinical presentation, diagnosis, management, and prognosis of NAFLD cirrhosis.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / diagnosis
  • Carcinoma, Hepatocellular / prevention & control*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / prevention & control
  • Esophageal and Gastric Varices / diagnosis
  • Esophageal and Gastric Varices / prevention & control
  • Humans
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / diagnosis*
  • Liver Cirrhosis / epidemiology*
  • Liver Cirrhosis / therapy
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / prevention & control*
  • Liver Transplantation
  • Non-alcoholic Fatty Liver Disease / complications
  • Non-alcoholic Fatty Liver Disease / epidemiology*
  • Population Surveillance*
  • Prevalence
  • Prognosis
  • Risk Factors