Infertility after abdominal trachelectomy

Acta Obstet Gynecol Scand. 2018 Nov;97(11):1358-1364. doi: 10.1111/aogs.13429. Epub 2018 Aug 28.

Abstract

Introduction: Despite numerous reports on pregnancy outcomes after trachelectomy, there are few descriptions of fertility treatment after trachelectomy. Moreover, little is known about the differences in fertility outcomes between various radical trachelectomy procedures. The purpose of this report was to clarify the infertility problems that occur in patients who have previously undergone an abdominal trachelectomy.

Material and methods: We retrospectively investigated the medical records of 37 patients who received fertility treatments or were evaluated for menstrual disorders after trachelectomies in our institution between 2012 and 2016.

Results: Twenty-two of 37 patients had complications which affected fecundity. Six patients had cervical stenosis requiring surgical dilation, 4 had ovarian insufficiency, and 14 had Asherman's syndrome.

Conclusions: In spite of efforts to preserve fertility, some patients have severe complications after trachelectomy, such as Asherman's syndrome, resulting in infertility. Clinicians should pay careful attention to the status of the endometrial cavity after trachelectomy.

Keywords: Asherman’s syndrome; infertility; trachelectomy; uterine cervical cancer.

MeSH terms

  • Adult
  • Female
  • Fertility Preservation
  • Follow-Up Studies
  • Humans
  • Infertility, Female / diagnosis
  • Infertility, Female / epidemiology
  • Infertility, Female / etiology*
  • Infertility, Female / therapy
  • Postoperative Complications* / diagnosis
  • Postoperative Complications* / epidemiology
  • Postoperative Complications* / therapy
  • Retrospective Studies
  • Trachelectomy*