Development and validation of a bedside instrument to predict carbapenem resistance among gram-negative pathogens in complicated urinary tract infections

Infect Control Hosp Epidemiol. 2018 Sep;39(9):1112-1114. doi: 10.1017/ice.2018.166. Epub 2018 Jul 31.

Abstract

We developed a bedside instrument to predict carbapenem resistance in complicated urinary tract infections. A model assigning weighted points for admission from an extended care facility (1), history of weight loss (1), early mechanical ventilation (1), age <50 years (2), male gender (3), catheter-associated urinary tract infection (4), prior antibiotics treatment (4), and prior carbapenem-resistant infection (8) exhibited good discrimination (C statistic, 0.721).

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Carbapenems / therapeutic use*
  • Catheter-Related Infections / complications
  • Catheter-Related Infections / microbiology
  • Cross Infection / drug therapy*
  • Female
  • Gram-Negative Bacterial Infections / drug therapy*
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Models, Theoretical
  • Prognosis
  • Retrospective Studies
  • Risk Assessment / methods
  • Severity of Illness Index
  • United States
  • Urinary Tract Infections / drug therapy*
  • Urinary Tract Infections / microbiology
  • beta-Lactam Resistance*

Substances

  • Anti-Bacterial Agents
  • Carbapenems