[Evaluation of renal function in the course of hypertension in the elderly]

Monika Rynkowska-Kidawa; Michał Kidawa; Joanna Kapusta; Robert Irzmański; Jan Kowalski

[Evaluation of renal function in the course of hypertension in the elderly]

Pol Merkur Lekarski. 2018 Jul 30;45(265):11-16.

[Article in Polish]

Authors

Monika Rynkowska-Kidawa¹, Michał Kidawa², Joanna Kapusta³, Robert Irzmański³, Jan Kowalski³

Affiliations

¹ Medical University of Lodz, MCM Jonscher, Łódź, Poland: Department of Internal Diseases and Geriatrics.
² Medical University of Lodz, MCM Jonscher, Łódź, Poland: Department of Cardiac Intensive Care.
³ Medical University of Lodz, MCM Jonscher, Łódź, Poland: Department of Internal Diseases and Cardiac Rehabilitation.

PMID: 30058621

Abstract

Hypertension is one of the most common chronic diseases in Poland. It occurs in all age groups, but most often affects people over 65 years of age. The correct diagnosis of hypertension in older people includes documenting elevated blood pressure values, differentiating disease changes from physiologically related changes to aging, as well as assessing organ related complications. Detection of organ complications is also an important parameter of prognosis assessment.

Aim: The aim of the study was evaluation of renal function in the course of hypertension in the elderly.

Materials and methods: The study involved 63 women and 17 men, aged from 75 to 93 years, who were diagnosed with arterial hypertension in accordance with the guidelines of the Polish Society of Hypertension. Patients were divided into two groups. The first pair consisted of a group of 1 hypertensive patients (HA) lasting up to 10 years of age over 85 years and a group of 2 patients with HA lasting up to 10 years at the age of 75-85 years. The second pair is group I - patients with HA over 10 years of age over 85 years and group II - patients with HA lasting over 10 years at the age of 75-85. The assessment of glomerular filtration was made using the estimated glomerular filtration rate (GFR), which was calculated according to the mathematical formula of MDRD, while the renal resistance index was assessed using spectral Doppler after visualization of the flow in the renal arteries.

Results: The value of glomerular filtration in the examined groups divided by age was 55.1±15 (group 1) and 66.9±16 (group 2). The values of the kidney artery resistance index (depending on age) were in 1 group: 0.61±0.04 vs 0.60±0.05 and in the second group: 0.59±0.06 vs 0.58±0.05. The values of the renal artery resistance index (depending on the duration of HA) were 0.62±0.04 vs 0.61±0.03 (group I) and 0.61±0.04 vs 0.60±0.04 ( group II).

Conclusions: GFR depends on the duration of hypertension. A relationship was found between the value of the kidney artery resistance index and age. There was no significant relationship between the value of the kidney artery resistance index and duration of hypertension.

Keywords: arterial hypertension; glomerular filtration rate; old age; renal resistance index.

MeSH terms

Aged
Aged, 80 and over
Female
Glomerular Filtration Rate
Humans
Hypertension / physiopathology*
Kidney / physiopathology*
Male