FcɛRI cross-linking and IL-3 protect human basophils from intrinsic apoptotic stress

J Allergy Clin Immunol. 2018 Nov;142(5):1647-1650.e3. doi: 10.1016/j.jaci.2018.06.040. Epub 2018 Jul 23.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aniline Compounds / pharmacology
  • Apoptosis / drug effects
  • Basophils / drug effects
  • Basophils / metabolism*
  • Caspase 3 / metabolism
  • Cells, Cultured
  • Eosinophils / drug effects
  • Humans
  • Indoles / pharmacology
  • Interleukin-3 / metabolism*
  • Myeloid Cell Leukemia Sequence 1 Protein / antagonists & inhibitors
  • Proto-Oncogene Proteins c-bcl-2 / antagonists & inhibitors
  • Receptors, IgE / metabolism*
  • Sulfonamides / pharmacology

Substances

  • A-1210477
  • Aniline Compounds
  • Indoles
  • Interleukin-3
  • MCL1 protein, human
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Proto-Oncogene Proteins c-bcl-2
  • Receptors, IgE
  • Sulfonamides
  • Caspase 3
  • navitoclax