Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj; Takao Ide; Aditi U Gurkar; Michael Foley; Monica Schenone; Xiaoyu Li; Nicola J Tolliday; Todd R Golub; Steven A Carr; Alykhan F Shamji; Andrew M Stern; Anna Mandinova; Stuart L Schreiber; Sam W Lee

doi:10.1038/s41586-018-0284-y

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Nature. 2018 Sep;561(7723):420. doi: 10.1038/s41586-018-0284-y.

Authors

Affiliations

¹ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
² Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
³ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. amandinova@partners.org.
⁴ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. amandinova@partners.org.
⁵ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. stuart_schreiber@harvard.edu.
⁶ Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. swlee@partners.org.
⁷ Broad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. swlee@partners.org.

Abstract

This Letter is being retracted owing to issues with Fig. 1d and Supplementary Fig. 31b, and the unavailability of original data for these figures that raise concerns regarding the integrity of the figures. Nature published two previous corrections related to this Letter^1,2. These issues in aggregate undermine the confidence in the integrity of this study. Authors Michael Foley, Monica Schenone, Nicola J. Tolliday, Todd R. Golub, Steven A. Carr, Alykhan F. Shamji, Andrew M. Stern and Stuart L. Schreiber agree with the Retraction. Authors Lakshmi Raj, Takao Ide, Aditi U. Gurkar, Anna Mandinova and Sam W. Lee disagree with the Retraction. Author Xiaoyu Li did not respond.

Publication types

Retraction of Publication