Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting

Biomicrofluidics. 2018 Jul 9;12(4):044104. doi: 10.1063/1.5038965. eCollection 2018 Jul.

Abstract

In this contribution, a channel aspect ratio of >2 was used to access high velocity regimes to provide confined sample cores by Dean focussing in advance of linear inertial focussing. This produces a singular separation origin with a mirrored transport path for efficient particle and blood cell sorting, while also increasing the spatial resolution for multiscale sorting.