IL-17 Takes Center Stage in Dermatophytosis

Florian Sparber; Salomé LeibundGut-Landmann

doi:10.1016/j.jid.2018.03.1518

IL-17 Takes Center Stage in Dermatophytosis

J Invest Dermatol. 2018 Aug;138(8):1691-1693. doi: 10.1016/j.jid.2018.03.1518.

Authors

Florian Sparber¹, Salomé LeibundGut-Landmann²

Affiliations

¹ Section of Immunology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.
² Section of Immunology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland. Electronic address: salome.leibundgut-landmann@uzh.ch.

PMID: 30032786
DOI: 10.1016/j.jid.2018.03.1518

Abstract

The cytokine IL-17 plays a critical role in host defense against fungal infections. So far, clinical relevance for IL-17 antifungal activity focused on mucocutaneous candidiasis. Burstein and colleagues now provide evidence that type 17 immunity is also essential for defense against dermatophytosis.

Publication types

Comment

MeSH terms

Candidiasis*
Candidiasis, Chronic Mucocutaneous*
Dermatomycoses*
Humans
Interleukin-17
Microsporum
Tinea*

Substances

Interleukin-17