Genetic analysis of 29 Y-STR loci in Han population from Dongfang, Southern China

Jian Zhang; Xiaoting Mo; Lei Shang; Xiuwen Jin; Dong Chen; Hongshan Zhu; Yiwen Zhang; Bin Kang; Wanshui Li; Jian Ye

doi:10.1007/s00414-018-1899-0

Genetic analysis of 29 Y-STR loci in Han population from Dongfang, Southern China

Int J Legal Med. 2019 Jul;133(4):1033-1035. doi: 10.1007/s00414-018-1899-0. Epub 2018 Jul 22.

Authors

Jian Zhang^#¹, Xiaoting Mo^#¹, Lei Shang¹, Xiuwen Jin², Dong Chen², Hongshan Zhu³, Yiwen Zhang¹, Bin Kang¹, Wanshui Li¹, Jian Ye⁴

Affiliations

¹ National Engineering Laboratory for Forensic Science, Beijing Engineering Research Center of Crime Scene Evidence Examination, Key Laboratory of Forensic Genetics, Ministry of Public Security, Institute of Forensic Science, Beijing, 100038, China.
² Dongfang Public Security Bureau, Dongfang, 000253, China.
³ Hainan Public Security Department, Haikou, China.
⁴ National Engineering Laboratory for Forensic Science, Beijing Engineering Research Center of Crime Scene Evidence Examination, Key Laboratory of Forensic Genetics, Ministry of Public Security, Institute of Forensic Science, Beijing, 100038, China. j.zhang@live.cn.

^# Contributed equally.

PMID: 30032460
DOI: 10.1007/s00414-018-1899-0

Abstract

In the present study, blood samples of 984 unrelated Han individuals were collected from Dongfang, Southern China, after informed consent. A total of 29 Y-chromosomal short tandem repeat (Y-STR) were analyzed, including DYF387S1, DYS19, DYS385ab, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS444, DYS447, DYS448, DYS449, DYS456, DYS458, DYS460, DYS481, DYS508, DYS518, DYS533, DYS576, DYS635, DYS643 and GATAH4. A total of 749 different haplotypes were found among 984 individuals, of which 645 were unique. The haplotype diversity was 0.9988 and the discrimination capacity was 0.7612, while the match probability was 0.0025. The smallest genetic distance (R_ST = 0.0155) was found between the Dongfang Han population and Guizhou Han population, while the largest genetic distance (R_ST = 0.1284) was observed with Gansu Tibetan.

Keywords: Dongfang Han; Genetic polymorphisms; Haplotypes; Y-STR.

MeSH terms

Asian People / genetics*
China
Chromosomes, Human, Y / genetics*
DNA / genetics
DNA Fingerprinting / methods
Genes, Y-Linked / genetics*
Haplotypes
Humans
Male
Microsatellite Repeats / genetics*

Substances

DNA