MGB-OAGB: Effect of Biliopancreatic Limb Length on Nutritional Deficiency, Weight Loss, and Comorbidity Resolution

Obes Surg. 2018 Nov;28(11):3439-3445. doi: 10.1007/s11695-018-3405-7.

Abstract

Introduction: Mini gastric bypass-one anastomosis gastric bypass (MGB-OAGB) has been approved as a mainstream metabolic/bariatric procedure by IFSO. Still there are lots of concerns regarding nutritional deficiency after MGB-OAGB. The purpose of this retrospective analysis is to evaluate the effect of biliopancreatic limb (BPL) length on weight loss, comorbidity resolution, and nutritional deficiencies in patients 1 year after MGB-OAGB and to find suitable BPL length.

Material and methods: One hundred and one patients who underwent MGB-OAGB were divided into three groups of 150 cm, 180 cm, and 250 cm depending on the length of BPL bypassed. The nutritional parameters (vitamin D3, vitamin B12, serum iron, serum ferritin, total protein, serum albumin, serum globulin), anthropometric measurements (weight, BMI), and comorbidity resolution (T2DM, hypertension) were compared between the three groups at 1-year follow-up.

Results: There was statistically significant difference in number of patients having deficiencies in all the nutritional parameters except globulin between 150 cm and 250 cm groups (P < 0.05). While on comparing 180- and 250-cm group, a statistically significant difference was present in vitamin D3, vitamin B12, and total protein (P < 0.05) only. The difference was statistically insignificant between the three groups on T2DM, hypertension resolution, and %EWL but TWL between 150 cm vs 180 cm and 150 cm vs 250 cm showed significant difference.

Conclusion: A 150-cm BPL length is adequate with very minimal nutritional complications and good results. A 180-cm BPL can be used in super obese while a 250-cm BPL should be used with utmost care as it results in significant nutritional deficiencies.

Keywords: Biliopancreatic limb (BPL); Body mass index (BMI); Common limb (CL); Mini gastric bypass-one anastomosis gastric bypass (MGB-OAGB); Percentage excess weight loss (%EWL); Roux-en-Y gastric bypass (RYGB); Total weight loss (TWL); Type 2 diabetes mellitus (T2DM).

MeSH terms

  • Comorbidity
  • Deficiency Diseases / epidemiology*
  • Gastric Bypass* / adverse effects
  • Gastric Bypass* / methods
  • Gastric Bypass* / statistics & numerical data
  • Humans
  • Obesity, Morbid* / epidemiology
  • Obesity, Morbid* / surgery
  • Weight Loss / physiology*