Background and objectives: Platelet concentrates are frequently transfused to patients with reduced immunity. An exhaustive description of their viral content is needed to prevent unwanted infection.
Material and methods: To track viral sequences, a shotgun metagenomics approach was used on a bank of 300 platelets concentrates. Sequences were analysed through the diagnostics-oriented pipeline ezVIR.
Results: We only observed viruses commonly described in healthy individuals.
Conclusion: Herein is reported the first viral landscape of a platelet concentrates bank.
Keywords: next-generation sequencing; platelet concentrates; transfusion-transmissible infections.
© 2018 International Society of Blood Transfusion.