[Protocol for the Prevention of Infections Related to the Treatment of Hematological Malignancies]

Acta Med Port. 2018 Jun 29;31(6):347-361. doi: 10.20344/amp.10035. Epub 2018 Jun 29.
[Article in Portuguese]

Abstract

Patients with haematological malignancies have a higher incidence of infection compared with the general population. Several factors contribute to this but specially chemotherapy drugs carry different and specific infectious risks. This protocol discusses the prevention of infections in patients who will undergo chemotherapy for the treatment of haematological malignancies. It is divided into: study prior to the initiation of chemotherapy; vaccination and eradication prior to initiation of chemotherapy; antimicrobial prophylaxis during chemotherapy; special situations. The main aims of this protocol are to serve as support to a more systematic and individualized approach to patients undergoing chemotherapy for the treatment of haematological malignancies and by doing so prevent the infectious complications that may arise.

Os doentes com doença hematológica neoplásica apresentam uma incidência de infeções superior à da população geral. Vários fatores contribuem para este aumento de incidência destacando-se os fármacos quimioterápicos que acarretam riscos infeciosos diferentes e específicos. Este protocolo versa a prevenção de infeções em doentes que vão ser submetidos a quimioterapia para tratamento de neoplasias hematológicas. Divide-se em: estudo prévio ao início de quimioterapia; vacinação e erradicações prévias ao início de quimioterapia; profilaxias antimicrobianas durante a quimioterapia; situações especiais. Pretende-se com este protocolo uma abordagem sistematizada e individualizada da situação clínica de cada doente de forma a prevenir de forma a prevenir de infeções emdoentes sob quimioterapia para tratamento de neoplasias hematológicas.

Keywords: Bacterial Infections/prevention & control; Community-Acquired Infections/prevention & control; Hematologic Neoplasms/ drug therapy.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Antineoplastic Agents / adverse effects*
  • Bacterial Infections / chemically induced
  • Bacterial Infections / immunology*
  • Bacterial Infections / prevention & control*
  • Clinical Protocols
  • Hematologic Neoplasms / drug therapy*
  • Hematologic Neoplasms / immunology
  • Humans
  • Practice Guidelines as Topic

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents