Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation

Oncologist. 2018 Nov;23(11):1385-1387. doi: 10.1634/theoncologist.2017-0223. Epub 2018 Jul 16.

Abstract

Pure seminoma is a histological subtype of testicular cancer that accounts for 50% of testicular germ cell tumors. It has a very low rate of metastasis to the central nervous system, with only one previously reported case of neoplastic meningitis (cancer that has spread to the cerebrospinal fluid). Traditionally, neoplastic meningitis has an ominous prognosis when associated with primary tumors that commonly spread to the leptomeninges, like breast and lung. This article highlights a unique case of pure seminoma with neoplastic meningitis and illustrates the effectiveness of craniospinal irradiation as a treatment modality.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Craniospinal Irradiation / methods*
  • Humans
  • Meningitis / etiology*
  • Meningitis / pathology
  • Meningitis / therapy*
  • Seminoma / complications*
  • Seminoma / pathology
  • Young Adult