Muscle fatigue in response to low-load blood flow-restricted elbow-flexion exercise: are there any sex differences?

Eur J Appl Physiol. 2018 Oct;118(10):2089-2096. doi: 10.1007/s00421-018-3940-x. Epub 2018 Jul 13.

Abstract

Purpose: This study aimed to determine whether men and women display a different magnitude of muscle fatigue in response to high-load (HL) and low-load blood flow-restricted (LLBFR) elbow-flexion exercise. We also explored to which extent both exercise protocols induce similar levels of muscle fatigue (i.e., torque decrement).

Methods: Sixty-two young participants (31 men and 31 women) performed dynamic elbow flexions at 20 and 75% of one-repetition maximum for LLBFR and HL exercise, respectively. Maximum voluntary isometric contractions were performed before and after exercise to quantify muscle fatigue.

Results: Men and women exhibited similar magnitude of relative torque decrement after both exercise protocols (p > 0.05). HL was more fatiguing (∆ torque output: 11.9 and 23 N.m in women and men, respectively) than LLBFR resistance exercise (∆ torque output: 8.3 and 15.4 N.m in women and men, respectively) in both sexes, but this was largely attenuated after controlling for the differences in volume load between protocols (p > 0.05).

Conclusions: These data show that torque decrement in response to LLBFR and HL dynamic elbow-flexion exercise does not follow a sexually dimorphic pattern. Our data also indicate that, if performed in a multiple-set fashion and prescribed for a given volume load, elbow-flexion LLBFR exercise induces similar levels of fatigue as HL acute training. Importantly, this occurs similarly in both sexes.

Keywords: Acute adaptation; Elbow flexion; KAATSU; Resistance training; Sexual dimorphism; Strength.

MeSH terms

  • Adult
  • Elbow / physiology*
  • Elbow Joint / physiology*
  • Electromyography / methods
  • Exercise / physiology*
  • Female
  • Humans
  • Isometric Contraction / physiology
  • Male
  • Muscle Fatigue / physiology*
  • Muscle, Skeletal / physiology*
  • Physical Endurance / physiology
  • Range of Motion, Articular / physiology
  • Regional Blood Flow / physiology*
  • Sex Characteristics
  • Torque
  • Young Adult