Mood instability contributes to impulsivity, non-suicidal self-injury, and binge eating/purging in people with anxiety disorders

Psychol Psychother. 2019 Sep;92(3):422-438. doi: 10.1111/papt.12192. Epub 2018 Jul 12.

Abstract

Objectives: The purpose of this study was to determine whether mood instability in people with anxiety disorders contributes to trait impulsivity, non-suicidal self-injury, and binge eating/purging.

Methods: Data were analysed from a general population sample of 7,221 adults (Mage = 51.0 years; 56.9% female). Logistic regression analyses with effect decompositions were used to establish the associations of five anxiety disorders (generalized anxiety disorder, social phobia, panic disorder, agoraphobia, and obsessive-compulsive disorder) with impulsivity, non-suicidal self-injury, and binge eating/purging, and then to determine the extent that adding mood instability to each model reduced these relationships.

Results: Participants with an anxiety disorder were more likely to report impulsivity compared to participants without an anxiety disorder (ORs = 2.40-3.92, all p < .001), but these relationships reduced by 59-78% and became non-significant when mood instability was added to the models. Participants with an anxiety disorder were also more likely to report non-suicidal self-injury (ORs = 3.86-18.9, all p < .001) and binge eating/purging (ORs = 4.05-14.9, all p < .01); adding mood instability to the models reduced these relationships by at least 30%.

Conclusions: Mood instability and impulsivity are common in people with anxiety disorders. Anxiety disorders are associated with impulsivity largely because of the association between mood instability and impulsivity. Mood instability may contribute to non-suicidal self-injury and binge eating/purging in people with anxiety disorders. Treatments for mood instability in addition to standard anxiety disorder treatment may reduce impulsivity, non-suicidal self-injury, and binge eating/purging in people with anxiety disorders.

Practitioner points: Many patients with anxiety disorders experience mood instability, which is associated with impulsivity, non-suicidal self-injury, and binge eating/purging. Treating mood instability alongside anxiety may help reduce impulsivity, non-suicidal self-injury, and binge eating/purging in people with anxiety disorders.

Keywords: affective instability; deliberate self-harm; eating disorders; self-injurious behaviour.

MeSH terms

  • Adult
  • Affective Symptoms / epidemiology
  • Affective Symptoms / physiopathology*
  • Aged
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / physiopathology*
  • Binge-Eating Disorder / epidemiology
  • Binge-Eating Disorder / physiopathology*
  • Comorbidity
  • Female
  • Humans
  • Impulsive Behavior / physiology*
  • Male
  • Middle Aged
  • Self-Injurious Behavior / epidemiology
  • Self-Injurious Behavior / physiopathology*
  • Young Adult