Improving childhood tuberculosis detection and treatment through facility-based screening in rural Pakistan

Int J Tuberc Lung Dis. 2018 Aug 1;22(8):851-857. doi: 10.5588/ijtld.17.0736.

Abstract

Setting: Many children with tuberculosis (TB) remain undiagnosed due to the absence of services, lack of child-friendly diagnostics and underappreciation of TB as a common cause of childhood illness.

Objective: To show the impact of systematic verbal screening and contact tracing with appropriate management services on TB case finding in pediatric populations.

Design: Between October 2014 and March 2016, children were verbally screened at the pediatric out-patient departments of four public hospitals in Jamshoro District, Pakistan. Children with symptoms or risk of TB were referred for clinical evaluation and free chest X-ray and bacteriological tests. Children with TB were started on treatment and their care givers asked to bring household members to the hospital for screening.

Results: Over 105 000 children were verbally screened and 5880 presumptive childhood TB patients were identified; 1417 children (prevalence 1.3%) were diagnosed with TB; 43% were female. The median age was 5 years; 82% had pulmonary TB. An additional 390 children with TB were diagnosed through contact tracing. These activities resulted in a three-fold increase in pediatric TB case notifications.

Conclusion: Systematic verbal screening with clinical evaluation and free diagnostics can identify children with TB who may otherwise be missed in rural health settings.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Contact Tracing / methods*
  • Family Characteristics
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mass Screening / economics
  • Mass Screening / methods*
  • Pakistan / epidemiology
  • Radiography, Thoracic / economics
  • Rural Population
  • Tuberculosis / diagnosis*
  • Tuberculosis / epidemiology