Marine Carbohydrate-Based Compounds with Medicinal Properties

Mar Drugs. 2018 Jul 9;16(7):233. doi: 10.3390/md16070233.

Abstract

The oceans harbor a great diversity of organisms, and have been recognized as an important source of new compounds with nutritional and therapeutic potential. Among these compounds, carbohydrate-based compounds are of particular interest because they exhibit numerous biological functions associated with their chemical diversity. This gives rise to new substances for the development of bioactive products. Many are the known applications of substances with glycosidic domains obtained from marine species. This review covers the structural properties and the current findings on the antioxidant, anti-inflammatory, anticoagulant, antitumor and antimicrobial activities of medium and high molecular-weight carbohydrates or glycosylated compounds extracted from various marine organisms.

Keywords: anti-inflammatory; anticoagulant; antimicrobial; antioxidant; antitumor; carbohydrate; glycoside; marine organisms.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology
  • Anticoagulants / chemistry
  • Anticoagulants / isolation & purification
  • Anticoagulants / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / isolation & purification
  • Antineoplastic Agents / pharmacology
  • Aquatic Organisms / chemistry*
  • Carbohydrates / chemistry
  • Carbohydrates / isolation & purification
  • Carbohydrates / pharmacology*
  • Glycosylation
  • Molecular Structure
  • Oceans and Seas
  • Structure-Activity Relationship

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Anticoagulants
  • Antineoplastic Agents
  • Carbohydrates