Saliva is being attached great importance for its application in illness diagnosis and have more advantage on the diagnose in oral cavity cancer (OCC). Studies have showed that interleukin (IL) in the saliva could be used as a potential biomarker for OCC diagnosis. Moreover, they have a close connection with tumor genesis, invasion, and metastasis in OCC. Therefore, we reviewed research progress on the relationship between salivary interleukins and OCC.
唾液用于疾病的诊断越来越受到重视，由于口腔癌（OCC）发生部位的特点，唾液中白细胞介素（IL）可作为OCC诊断的生物标志物，并与OCC的发生、发展、侵袭、转移密切相关。本文对唾液中IL的检测方法及其与OCC发生、发展的关系等方面的研究进展进行综述。.
Keywords: biomarker; interleukin; oral cavity cancer; saliva.