eXamine: Visualizing annotated networks in Cytoscape

F1000Res. 2018 Apr 30:7:519. doi: 10.12688/f1000research.14612.2. eCollection 2018.

Abstract

eXamine is a Cytoscape app that displays set membership as contours on top of a node-link layout of a small graph. In addition to facilitating interpretation of enriched gene sets of small biological networks, eXamine can be used in other domains such as the visualization of communities in small social networks. eXamine was made available on the Cytoscape App Store in March 2014, has since registered more than 7,700 downloads, and has been highly rated by more than 25 users. In this paper, we present eXamine's new automation features that enable researchers to compose reproducible analysis workflows to generate visualizations of small, set-annotated graphs.

Keywords: Euler diagram; enrichment; functional subnetwork modules; graph drawing; network community; visualization.

Grants and funding

The author(s) declared that no grants were involved in supporting this work.