Endothelial cells: The heart attack of the Clones

Gaetano Santulli

doi:10.1126/scitranslmed.aar7529

Endothelial cells: The heart attack of the Clones

Sci Transl Med. 2018 Feb 7;10(427):eaar7529. doi: 10.1126/scitranslmed.aar7529.

Author

Gaetano Santulli¹

Affiliation

¹ Department of Medicine, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USA. Department of Advanced Biomedical Sciences, "Federico II" University of Naples, Naples 80131, Italy.

Abstract

Neovascularization induced by acute myocardial infarction is mediated by clonal expansion of mature endothelial cells, which is triggered by VEGFR-2 signaling.

Publication types

Comment

MeSH terms

Cells, Cultured
Endothelial Cells*
Humans
Ischemia
Myocardial Infarction*
Neovascularization, Pathologic

Grants and funding

R00 DK107895/DK/NIDDK NIH HHS/United States