Mother-to-child transmission of hepatitis C virus

Minerva Pediatr. 2019 Apr;71(2):174-180. doi: 10.23736/S0026-4946.18.04898-3. Epub 2018 Jul 2.

Abstract

This review reinforces the lack of a single maternal risk factor that is highly associated with vertical transmission (VT) of the infection with hepatitis C virus (HCV): indeed HCV RNA levels, mode of delivery, breast feeding, viral genotype or maternal IL28B status were not associated with HCV VT.

Publication types

  • Review

MeSH terms

  • Breast Feeding / statistics & numerical data
  • Delivery, Obstetric / statistics & numerical data
  • Female
  • Genotype
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification
  • Hepatitis C / transmission*
  • Humans
  • Infectious Disease Transmission, Vertical*
  • Interferons
  • Interleukins / genetics
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / virology*
  • Risk Factors

Substances

  • interferon-lambda, human
  • Interleukins
  • Interferons