Two-photon fluorescent probe with enhanced absorption cross section for relay recognition of Zn2+/P2O74- and in vivo imaging

Ying Xia; Huihui Zhang; Xiaojiao Zhu; Qiong Zhang; Min Fang; Xiaowu Li; Hongping Zhou; Xingyuan Yang; Xuanjun Zhang; Yupeng Tian

doi:10.1016/j.saa.2018.06.065

Two-photon fluorescent probe with enhanced absorption cross section for relay recognition of Zn²⁺/P₂O₇^4- and in vivo imaging

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Nov 5:204:446-451. doi: 10.1016/j.saa.2018.06.065. Epub 2018 Jun 27.

Authors

Affiliations

¹ College of Chemistry and Chemical Engineering, Anhui University and Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, 230601 Hefei, PR China.
² College of Chemistry and Chemical Engineering, Anhui University and Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province, Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials, 230601 Hefei, PR China. Electronic address: zhpzhp@263.net.
³ Institute of Physical Science and Information Technology, Faculty of Health Sciences, Anhui University, Hefei 230601, PR China.
⁴ Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, PR China.

PMID: 29966899
DOI: 10.1016/j.saa.2018.06.065

Abstract

A novel multifunctional probe, L, based on triphenylamine o-hydroxyl Schiff base was constructed for the sequential detection of Zn²⁺/P₂O₇^4-. Interestingly, probe L also showed two-photon fluorescent "off-on" response to Zn²⁺ along with a large effective two-photon absorption cross-section value of 240 GM at 720 nm, a low cytotoxic and a moderate photostability, which made L a good candidate for two-photon fluorescence microscopy imaging and monitoring the fluctuation of exogenous Zn²⁺.

Keywords: Exogenous; Fluorescence probe; Two-photon; Zinc ion.

Publication types

Review