Killer cell immunoglobulin-like receptor genotypes in a Chilean population from Talca

Hum Immunol. 2018 Sep;79(9):651-652. doi: 10.1016/j.humimm.2018.06.007. Epub 2018 Jun 28.

Abstract

Ninety healthy and unrelated volunteers were randomly selected to study the gene frequencies of Killer-cell immunoglobulin-like receptors (KIRs) in a Chilean (Talca) population. KIR typing was resolved by PCR-single specific primer (SSP), and their gene frequencies were calculated by direct counting of the number of positive and negative loci. The KIR genotype data is publicly available in the Allele Frequencies Net Database under the name "Chile Talca KIR".

MeSH terms

  • Adult
  • Chile
  • Ethnicity
  • Female
  • Gene Frequency
  • Genetics, Population
  • Genotype*
  • Healthy Volunteers
  • Histocompatibility Testing
  • Humans
  • Killer Cells, Natural / physiology*
  • Male
  • Polymorphism, Genetic
  • Receptors, KIR / genetics*

Substances

  • Receptors, KIR