Innovative Surveillance Strategies to Support the Elimination of Filariasis in Africa

Trends Parasitol. 2018 Aug;34(8):694-711. doi: 10.1016/j.pt.2018.05.004. Epub 2018 Jun 26.

Abstract

Lymphatic filariasis (LF) and onchocerciasis are two neglected tropical diseases (NTDs) of public health significance targeted for global elimination. The World Health Organization (WHO) African Region is a priority region, with the highest collective burden of LF and onchocerciasis globally. Coendemic loiasis further complicates elimination due to the risk of adverse events associated with ivermectin treatment. A public health framework focusing on health-related data, systematic collection of data, and analysis and interpretation of data is used to highlight the range of innovative surveillance strategies required for filariasis elimination. The most recent and significant developments include: rapid point-of-care test (POCT) diagnostics; clinical assessment tools; new WHO guidelines; open-access online data portals; mHealth platforms; large-scale prevalence maps; and the optimisation of mathematical models.

Keywords: Africa; elimination; loiasis; lymphatic filariasis; onchocerciasis; surveillance.

Publication types

  • Review

MeSH terms

  • Africa
  • Disease Eradication*
  • Elephantiasis, Filarial / prevention & control*
  • Humans
  • Public Health Surveillance / methods*
  • Tropical Medicine
  • World Health Organization