Abstract
Hepatic fibrosis is a common feature of almost all chronic liver diseases. Formation of new vessels (angiogenesis) is a process strictly related to the progressive fibrogenesis which leads to cirrhosis and liver cancer. This review mainly concerns the relationship between angiogenesis and hepatic fibrosis, by considering the mechanism of angiogenesis, cells in angiogenesis, anti-angiogenic and Chinese medicine therapies.
Keywords:
Chinese medicine; angiogenesis; hepatic fibrosis; review.
MeSH terms
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Angiogenesis Inhibitors / therapeutic use
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Animals
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Drugs, Chinese Herbal / therapeutic use*
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Hepatic Stellate Cells / drug effects
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Humans
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Liver Cirrhosis / drug therapy*
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Liver Cirrhosis / etiology
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Medicine, Chinese Traditional*
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Neovascularization, Pathologic / complications*
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Vascular Endothelial Growth Factor A / antagonists & inhibitors
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Vascular Endothelial Growth Factor A / physiology
Substances
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Angiogenesis Inhibitors
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Drugs, Chinese Herbal
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Vascular Endothelial Growth Factor A