A geometric model for the human pulmonary valve in its fully open case

PLoS One. 2018 Jun 25;13(6):e0199390. doi: 10.1371/journal.pone.0199390. eCollection 2018.

Abstract

The human pulmonary valve, one of the key cardiac structures, plays an important role in circulatory system. However, there are few mathematical models to accurately simulate it. In this paper, we establish a geometric model of the normal human pulmonary valve from a mathematical perspective in the fully opening case. Based on the statistical data of the human pulmonary valves, we assume that the motions of the three cusps are symmetrical in the cardiac cycle. Thus, we first propose that each cusp is a part of the cylindrical shell according to its structure and physiological feature. The parameters for the pulmonary valve cusps in three-dimensional space are obtained by the fitting functions. We verify the accuracy of our results by comparing the areas of the pulmonary valve and pulmonary valve flap.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Imaging, Three-Dimensional
  • Models, Anatomic*
  • Pulmonary Valve / anatomy & histology*
  • Pulmonary Valve / physiology*
  • Reproducibility of Results

Grants and funding

This paper is supported by National Natural Science Foundation of China (NO.11571275, 11572244, 11471261) and by the Natural Science Foundation of Shaanxi Province (NO. 2018JM1014). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.