Peritoneal Metastases from Malignant Mesothelioma

Surg Oncol Clin N Am. 2018 Jul;27(3):539-549. doi: 10.1016/j.soc.2018.02.010.

Abstract

Diffuse malignant peritoneal mesothelioma (MPM) is a rare cancer that is ultimately fatal in almost all afflicted individuals. Morbidity and mortality from MPM is due to its propensity to progress locoregionally within the abdominal cavity. Patients with MPM most commonly present with nonspecific abdominal symptoms that usually lead to diagnosis when the condition is relatively advanced. MPM is considered a chemotherapy-resistant malignancy.

Keywords: Diffuse malignant peritoneal mesothelioma; Early postoperative intraperitoneal chemotherapy; Hyperthermic intraoperative peritoneal chemotherapy; Operative cytoreduction; Peritoneal metastases.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy
  • Humans
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / therapy*
  • Mesothelioma / pathology*
  • Mesothelioma / therapy*
  • Mesothelioma, Malignant
  • Peritoneal Neoplasms / secondary*
  • Peritoneal Neoplasms / therapy*
  • Treatment Outcome