Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion

Cell Res. 2018 Aug;28(8):865-867. doi: 10.1038/s41422-018-0057-z. Epub 2018 Jun 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cells, Cultured
  • Fibroblasts / metabolism
  • GTP Phosphohydrolases / metabolism
  • Gene Knockdown Techniques
  • Glutaminase / genetics
  • Glutaminase / physiology*
  • Glutamine / deficiency
  • Glutamine / metabolism*
  • Mitochondria / physiology*
  • Mitochondrial Dynamics*
  • Peroxisomal Multifunctional Protein-2 / metabolism
  • Reactive Oxygen Species / metabolism

Substances

  • Reactive Oxygen Species
  • Glutamine
  • Hsd17b4 protein, mouse
  • GLS1 protein, mouse
  • Glutaminase
  • GTP Phosphohydrolases
  • Mfn1 protein, mouse
  • Opa1 protein, mouse
  • Peroxisomal Multifunctional Protein-2