Anti-Fatigue Effects of Yogurt Fermented with Lactobacillus delbureckii subsp. bulgaricus OLL1073R-1 in Healthy People Suffering from Summer Heat Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients. 2018 Jun 21;10(7):798. doi: 10.3390/nu10070798.

Abstract

Fatigue caused by summer heat is a typical indefinite complaint along with anorexia, loss of sleep, stress, lack of motivation and, in some cases, catching a cold. Yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 has been shown to stimulate the immune system and reduce the risk of catching colds. Here, we conducted a randomized, double-blinded, placebo-controlled trial to investigate whether ingesting this yogurt could ameliorate summer heat fatigue in 49 healthy males (median age 40.0 ± 6.0 years; 30⁻49 years) who felt fatigued every summer. Fatigue was evaluated by visual analogue scales (VAS) and the balance of sympathetic/parasympathetic nervous systems. After 12 weeks of ingestion in early autumn, the VAS fatigue scores in the yogurt group were lower than those of the placebo group. These results indicate that yogurt fermented with L. bulgaricus OLL1073R-1 can ameliorate summer heat fatigue lasting up to early autumn.

Keywords: anti-fatigue; stress; summer heat; yogurt.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Body Mass Index
  • Cross-Over Studies
  • Dietary Carbohydrates / analysis
  • Dietary Fats / analysis
  • Dietary Proteins / analysis
  • Double-Blind Method
  • Fatigue / etiology
  • Fatigue / therapy*
  • Hot Temperature / adverse effects*
  • Humans
  • Killer Cells, Natural / metabolism
  • Lactobacillus delbrueckii*
  • Male
  • Middle Aged
  • Surveys and Questionnaires
  • Treatment Outcome
  • Yogurt / microbiology*

Substances

  • Dietary Carbohydrates
  • Dietary Fats
  • Dietary Proteins