Association of Glycemic Control and Cell Stress With Telomere Attrition in Type 1 Diabetes

Tine Tesovnik; Jernej Kovac; Tinka Hovnik; Klemen Dovc; Nataša Bratina; Tadej Battelino; Katarina Trebušak Podkrajšek

doi:10.1001/jamapediatrics.2018.1175

Association of Glycemic Control and Cell Stress With Telomere Attrition in Type 1 Diabetes

JAMA Pediatr. 2018 Sep 1;172(9):879-881. doi: 10.1001/jamapediatrics.2018.1175.

Authors

Tine Tesovnik¹, Jernej Kovac², Tinka Hovnik², Klemen Dovc¹, Nataša Bratina¹, Tadej Battelino¹, Katarina Trebušak Podkrajšek²

Affiliations

¹ Department for Endocrinology, Diabetes and Metabolic Disorders, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.
² Unit of Special Laboratory Diagnostics, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Abstract

This longitudinal study evaluates the association of glycemic control and associated cell stress with the telomere dynamics in a pediatric population with type 1 diabetes during a 7-year follow-up.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Blood Glucose / metabolism*
Diabetes Mellitus, Type 1 / metabolism*
Female
Humans
Male
Telomere / metabolism*
Telomere Shortening*

Substances

Blood Glucose