Chemical and Physicochemical Properties of Gangliosides

Laura Mauri; Sandro Sonnino; Alessandro Prinetti

doi:10.1007/978-1-4939-8552-4_1

Chemical and Physicochemical Properties of Gangliosides

Methods Mol Biol. 2018:1804:1-17. doi: 10.1007/978-1-4939-8552-4_1.

Authors

Laura Mauri¹, Sandro Sonnino¹, Alessandro Prinetti²

Affiliations

¹ Department of Medical Biotechnology and Translational Medicine, The Medical School, University of Milano, Milano, Italy.
² Department of Medical Biotechnology and Translational Medicine, The Medical School, University of Milano, Milano, Italy. alessandro.prinetti@unimi.it.

PMID: 29926402
DOI: 10.1007/978-1-4939-8552-4_1

Abstract

In this chapter, we briefly describe the structural features of gangliosides, and focus on the peculiar chemicophysical features of gangliosides, an important class of membrane amphipathic lipids that represent an important driving force determining the organization and properties of cellular membranes.

Keywords: Ceramide; Gangliosides; Glycosphingolipids; Lipid rafts; Sphingosine.

Publication types

Review

MeSH terms

Chemical Phenomena*
Gangliosides / chemistry*
Molecular Conformation

Substances

Gangliosides