Objective: To review the basical research progress of porous tantalum in bone tissue engineering.
Methods: The related basical research in fabrication, cytobiology, and surface modification of porous tantalum was reviewed and analyzed.
Results: The outstanding physiochemical properties of porous tantalum granted its excellent performance in biocompatibility and osteointegration, as well as promoting cartilage and tendon tissue restoration. However, the clinical utilization of porous tantalum is somehow greatly limited by the complex and rigid commercial fabrication methods and extraordinary high cost. Along with the publication of novel fabrication and surface modification technology, the application of porous tantalum will be more extensive, the promotion in bone tissue regeneration will be more prominent.
Conclusion: Porous tantalum has advantage in bone defect restoration, and significant breakthrough technology is needed in fabrication methods and surface modification.
目的: 对多孔钽在骨组织工程中的研究进展作一综述。.
方法: 查阅近年多孔钽在制备、细胞生物学、表面修饰等领域的基础研究文献，并总结分析。.
结果: 多孔钽自身特有的理化性质赋予其良好的组织相容性、骨整合能力，并可诱导软骨、肌腱修复再生。目前因多孔钽制备条件苛刻、成本较高等因素，限制了其临床广泛应用；新的制备方法及表面修饰技术的发展，为拓展多孔钽的应用范围，优化其骨组织修复再生能力提供了新的路径。.
结论: 多孔钽在修复骨缺损方面具有独特优势，但仍需在材料制备及表面修饰方面有进一步突破。.
Keywords: Porous tantalum; bone tissue enginnering; osteointegration; surface modification.