•Sudden cardiac arrest can be a form of carboplatin hypersensitivity reaction.•Platinum retreatment and cumulative cycles of ≥ 8 are risk factors.•Awareness of the reaction related to carboplatin infusion is necessary.•Successful resuscitation with high quality CPR is achievable with trained staffs.
Keywords: Anaphylactic shock; Cardiac arrest; Ovarian cancer; Platinum.