Dysphagia due to macroglossia in a patient with amyloidosis associated with multiple myeloma: A case report

Spec Care Dentist. 2018 Jul;38(4):255-258. doi: 10.1111/scd.12299. Epub 2018 Jun 11.

Abstract

Amyloidosis is a group of heterogeneous conditions characterized by the deposition of extracellular proteinaceous substances called amyloids. The diagnosis is usually confirmed after a particular body organ has been affected. However, oral manifestations have been identified in 39% of affected patients. Systemic amyloidosis may be primary or in association with multiple myeloma and typically affecting elder adults. The diagnosis of amyloidosis is usually associated with clinical features with histopathological findings, which reveal the presence of acellular eosinophilic deposits. The aim of this report is to describe a clinical case of an elderly patient with dysphagia related to macroglossia and enlargement caused by primary amyloidosis associated with multiple myeloma.

Keywords: amyloid deposits; amyloidosis; multiple myeloma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amyloidosis / complications*
  • Deglutition Disorders / etiology*
  • Diagnosis, Differential
  • Fatal Outcome
  • Humans
  • Macroglossia / etiology*
  • Male
  • Multiple Myeloma / complications*