Conjunctival bleb compression sutures: An effective method of addressing hypotony after trabeculectomy or trabeculectomy-related procedures

Eur J Ophthalmol. 2018 Nov;28(6):731-734. doi: 10.1177/1120672118777100. Epub 2018 Jun 11.

Abstract

Purpose:: Over-filtration is a well-known complication of trabeculectomy and related procedures, especially with adjunctive antimetabolites. Secondary hypotony can result in reduced visual acuity and compromise long-term surgical success. Persistent hypotony requires intervention and we describe an effective adaptation of placing conjunctival compression sutures directly over the scleral flap.

Methods:: A retrospective consecutive case series of all patients who underwent conjunctival compression suturing from 2012 to 2014 at Manchester Royal Eye Hospital, UK. Under sub-tenon's anaesthesia, two 9/0 nylon figure-of-eight transconjunctival sutures were placed horizontally across the bleb: the first over the anterior flap/ostium and the second over the posterior flap edge to reduce flow through the trabeculectomy flap.

Results:: A total of 10 patients underwent conjunctival compression suturing, and all patients had successful reversal of hypotony and symptom resolution within 1 week with corresponding clinical improvement. Intraocular pressure control was maintained without topical pressure-lowering agents in seven patients (median = 10 mmHg, range = 7-12 mmHg) with a median follow-up of 35.9 months (range = 11-61 months). Two patients required topical therapy to maintain intraocular pressure ≤ 14 mmHg and one patient's hypotony returned after 10 months but remained untreated due to pre-existing poor vision. No patients required a return to theatre.

Conclusion:: This series demonstrates that conjunctival compression sutures can successfully provide long-term control of trabeculectomy-bleb-related hypotony. This technique offers an effective alternative for glaucoma surgeons in addressing post-trabeculectomy hypotony.

Keywords: Conjunctival compression sutures; hypotony; trabeculectomy; trabeculectomy complication.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blister
  • Conjunctiva / surgery
  • Conjunctival Diseases / surgery*
  • Female
  • Filtering Surgery / methods*
  • Glaucoma / surgery*
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Ocular Hypotension / prevention & control*
  • Retrospective Studies
  • Sclera / surgery
  • Surgical Flaps
  • Suture Techniques*
  • Tonometry, Ocular
  • Trabeculectomy / methods*