[Progress in Research Drug Eluting Stents Drug-looding and Drug Release Kinetics]

Zhongguo Yi Liao Qi Xie Za Zhi. 2018 May 30;42(3):193-197. doi: 10.3969/j.issn.1671-7104.2018.03.011.
[Article in Chinese]

Abstract

Drug eluting stents are one of the main devices of coronary intervention, which play a therapeutic role through the combination of medical devices. Drug is an important part of the drug eluting stents. The loading method, the type of carrier, drug and carrier interaction and the preparation process of the drug directly affect the drugs release kinetics characteristics of the device and the final treatment. According to the characteristics of the drug coating, drug coated stents can be divided into non-degradable polymers drug coated stents, biodegradable polymers drug coated stents and polymer-free drug eluting stents. This article discussed the stent coating process and drug release kinetics of the three types of drug eluting stent.

Keywords: coating method; drug eluting stent; release kinetics.

MeSH terms

  • Drug Liberation*
  • Drug-Eluting Stents*
  • Kinetics
  • Polymers
  • Stents

Substances

  • Polymers