Persecutory delusions: effects of Cognitive Bias Modification for Interpretation and the Maudsley Review Training Programme on social anxiety, jumping to conclusions, belief inflexibility and paranoia

J Behav Ther Exp Psychiatry. 2018 Dec:61:14-23. doi: 10.1016/j.jbtep.2018.05.003. Epub 2018 May 9.

Abstract

Background and objectives: The Threat Anticipation Model (Freeman, 2007) implicates social anxiety, jumping to conclusions (JTC) and belief inflexibility in persecutory delusions. We investigated whether Cognitive Bias Modification for Interpretation (CBM-I; Turner et al., 2011) improves social anxiety by targeting negative interpretation bias of ambiguous social information. We determined whether the Maudsley Review Training Programme (MRTP; Waller et al., 2011) improves JTC, belief inflexibility and paranoia. We also explored effects of CBM-I on JTC/belief inflexibility and paranoia, as well as the MRTP on social anxiety.

Methods: Twelve participants from Early Intervention and Recovery Services in East Anglia completed measures of social anxiety, paranoia, JTC and belief inflexibility. A concurrent multiple baseline case series design was used.

Results: Three of twelve participants improved in social anxiety following CBM-I, paranoia improved in 6/12 cases. CBM-I had no effect on JTC/belief inflexibility. The MRTP improved JTC and/or belief inflexibility in 9/12 cases, while improving paranoia for 6/12 individuals. The MRTP improved social anxiety in one case.

Limitations: The small sample size and large effects necessary for single case series designs limit the generality of findings. These are discussed in more detail.

Conclusions: This study suggests that whilst both CBM-I and the MRTP may have a positive impact on paranoia and social anxiety, the effects on JTC/belief inflexibility are largely specific to the MRTP. Relationships between social anxiety, JTC, belief inflexibility and paranoia existed in 10/12 individuals, supporting the Threat Anticipation Model.

Keywords: Cognitive bias modification for interpretation; Jumping to conclusions; Persecutory delusions; Psychosis; Social anxiety; The Maudsley review training program.

MeSH terms

  • Adult
  • Anxiety / physiopathology*
  • Anxiety / therapy*
  • Cognitive Behavioral Therapy / methods*
  • Community Mental Health Services
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paranoid Disorders / physiopathology*
  • Paranoid Disorders / therapy*
  • Program Development*
  • Schizophrenia, Paranoid / physiopathology*
  • Schizophrenia, Paranoid / therapy*
  • Thinking / physiology*
  • Treatment Outcome
  • Young Adult