Chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin improved spontaneous pneumothorax and thoracic endometriosis: The first case involving a pregnant woman

Taiwan J Obstet Gynecol. 2018 Jun;57(3):449-451. doi: 10.1016/j.tjog.2018.04.022.

Abstract

Objective: Spontaneous pneumothorax combined with thoracic endometriosis is a rare condition during pregnancy. We present a case of chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin during pregnancy.

Case report: This report presents a case of spontaneous pneumothorax combined with thoracic endometriosis that arose at 22 weeks' gestation in a 35-year-old female. The initial chest drainage was unsuccessful. At 25 weeks' gestation, video-assisted thoracoscopic surgery was performed and revealed endometriosis in the thoracic cavity. Since the leak persisted, chemical pleurodesis was performed with autologous blood and freeze-dried concentrated human thrombin at 28 weeks' gestation. The leak improved markedly and did not recur.

Conclusion: This is the first case report about chemical pleurodesis with autologous blood and freeze-dried concentrated human thrombin during pregnancy. This procedure might contribute to the management of pneumothorax in pregnant women.

Keywords: Autologous blood; Chemical pleurodesis; Pneumothorax; Pregnancy; Thoracic endometriosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Transfusion, Autologous*
  • Endometriosis / complications
  • Endometriosis / diagnosis
  • Female
  • Hemostatics / administration & dosage*
  • Humans
  • Pleurodesis*
  • Pneumothorax / complications
  • Pneumothorax / diagnostic imaging
  • Pneumothorax / surgery
  • Pneumothorax / therapy*
  • Pregnancy
  • Pregnancy Complications / therapy*
  • Thoracic Diseases / complications
  • Thoracic Diseases / diagnosis
  • Thoracic Surgery, Video-Assisted
  • Thrombin / administration & dosage*

Substances

  • Hemostatics
  • Thrombin