Rationale: Colonic lipomas are uncommon benign submucosal adipose tumorsthat are usually asymptomatic. Large lipomas can cause symptoms require treatment in principle. We report 1 case of giant colonic lipoma removed with endoloop-assisted unroofing technique instead of conventional surgical bowel resection.
Patient concerns: A 62-year-old female patient presented with intermittent abdominal discomfort for 1 month.
Diagnosis: The patient was diagnosed as having a giant colonic lipoma.
Intervention: Endoscopic resection with endoloop-assisted unroofing technique was performed. On the 22nd day after resection, intestinal obstruction occurred by shedding mass was found; the symptoms of this patient disappeared soon after removal of the mass by endoscopy.
Outcomes: A follow-up colonoscopy 6 months later showed a scarred mucosa at the ligation site and no residual lipoma was observed.
Lessons: Endoscopic resection with endoloop-assisted unroofing technique remains a viable option for giant lipomas; however, postoperative intestinal obstruction caused by shedding mass should be noted.