RNA sequencing data of Notch ligand treated human dental pulp cells

Jeeranan Manokawinchoke; Praphawi Nattasit; Tanutchaporn Thongngam; Prasit Pavasant; Kevin A Tompkins; Hiroshi Egusa; Thanaphum Osathanon

doi:10.1016/j.dib.2018.01.058

RNA sequencing data of Notch ligand treated human dental pulp cells

Data Brief. 2018 Jan 31:17:407-413. doi: 10.1016/j.dib.2018.01.058. eCollection 2018 Apr.

Authors

Jeeranan Manokawinchoke^{1

2}, Praphawi Nattasit¹, Tanutchaporn Thongngam¹, Prasit Pavasant^{1

2}, Kevin A Tompkins^{1

3}, Hiroshi Egusa⁴, Thanaphum Osathanon^{1

2

5}

Affiliations

¹ Excellence Center in Regenerative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
² Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
³ Office of Research Affairs, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
⁴ Division of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan.
⁵ Craniofacial Genetics and Stem Cells Research Group, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.

Abstract

Indirect immobilized ligand has been shown as an effective technique to activate Notch signalling in vitro. The data presented in this article are related to the published article entitled "Indirect immobilized Jagged1 suppresses cell cycle progression and induces odonto/osteogenic differentiation in human dental pulp cells" (Manokawinchoke et al. 2017) [1]. This data article describes gene expression in indirect immobilized Jagged1 treated human dental pulp cells (hDPs) using high throughput RNA sequencing technique. These data are valuable to analyze the regulation of Notch signalling in hDPs for understanding its molecular mechanism(s). Raw RNA sequencing data were deposited in the NCBI Sequence Read Archive (SRP100068) and NCBI Gene Expression Omnibus (GSE94989).