Posterior Reversible Encephalopathy Syndrome as a Postpartum Complication

Open Access Maced J Med Sci. 2018 May 14;6(5):851-854. doi: 10.3889/oamjms.2018.193. eCollection 2018 May 20.

Abstract

Background: Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome with seizures, altered consciousness, visual disturbances and headache among other symptoms. Hinchey et al. first described Pres in 1996, with two other case series published shortly after.

Case report: A 23-year-old women patient was emergency sent from General Hospital Tešanj due to a crisis of consciousness and repeated epileptic seizures. The patient had a second birth before 10 days (postpartum cesarean) in general endotracheal anaesthesia (two cesarean-born babies). On magnetic resonance imaging (MRI) of cranium described both sides of the symmetrically frontal, parietal (and pre-ventricular gyri) and occipitally visible T2W/FLAIR hyperintensity focuses on the cortex and the thin layer of white mass subcortically. In the projection of the lesions parts, discrete DWI hyperintensity is seen without a reliable ADC correlate. The patient improved after management with intravenous fluids, antibiotics, antiepileptics and monitoring of blood pressure. According to latest experiences delayed diagnosis and treatment may lead to mortality or irreversible neurological deficit. Aggravating circumstances are differential diagnoses that include cerebral infarction (ischemic, haemorrhage), venous thrombosis, vasculitis, pontine or extrapontine myelinolysis.

Conclusion: MRI of the brain is key to make this distinction with crucial recognition and an open mind from radiology and neurology specialist.

Keywords: Cortical blindness; Epileptic seizures; MRI; Posterior reversible encephalopathy syndrome (PRES); Postpartum cesarean.

Publication types

  • Case Reports