Theranostics of Gold Nanoparticles with an Emphasis on Photoacoustic Imaging and Photothermal Therapy

Curr Pharm Des. 2018;24(23):2719-2728. doi: 10.2174/1381612824666180604112201.

Abstract

Gold nanoparticles (AuNPs) are promising biomedical agents in terms of both imaging and therapy, exhibiting excellent physical and chemical characteristics. The actions of AuNPs can be remotely controlled using strong near-infrared (NIR) light, associated with minimal lateral invasion. Employing the photoacoustic (PA) principle, AuNPs integrate imaging and temperature control, affording both diagnosis and treatment mediated by NIR light. We here review recent progress in the theranostic field employing AuNPs to both PA and photothermal ends.

Keywords: Gold nanoparticles; minimal lateral invasion; photoacoustic (PA) principle; photoacoustic imaging; photothermal therapy; theranostics..

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / drug therapy*
  • Glioma / diagnostic imaging*
  • Glioma / drug therapy*
  • Gold / chemistry
  • Humans
  • Metal Nanoparticles / chemistry*
  • Photoacoustic Techniques*
  • Phototherapy*
  • Theranostic Nanomedicine*

Substances

  • Gold