[Research Progress of Bioresorbable Scaffold]

Zhongguo Yi Liao Qi Xie Za Zhi. 2017 Sep 30;41(5):357-361. doi: 10.3969/j.issn.1671-7104.2017.05.012.
[Article in Chinese]

Abstract

Bioresorbable scaffold (BRS) represents a new technique for percutaneous coronary intervention (PCI). Through providing temporary support to the vessel, it guarantees patency and acute benefits of the vessel in the early treatment stage. When completing its "mission", BRS gradually disappears by resorption. So it allows late vessel positive remodeling without "metal cage" effect and leaves only healed natural vessel after the full absorption, especially in the bifurcation lesion, the branch of the vessels can eventually achieve stent-free interference. This unique performance can not be achieved by the traditional permanent metal stent, so BRS has attracted more and more attention since its appearance. This article reviewed the research background, current status and challenges of BRS, then discussed its future development trends.

Keywords: bioresorbable scaffold (BRS); percutaneous coronary intervention (PCI); vascular endothelial cell (VEC); vascular stent.

Publication types

  • Review

MeSH terms

  • Absorbable Implants*
  • Coronary Artery Disease
  • Coronary Vessels
  • Drug-Eluting Stents
  • Humans
  • Percutaneous Coronary Intervention*
  • Prosthesis Design
  • Tissue Scaffolds*
  • Treatment Outcome