Correlation between Na/K ratio and electron densities in blood samples of breast cancer patients

Biometals. 2018 Aug;31(4):673-678. doi: 10.1007/s10534-018-0118-2. Epub 2018 May 31.

Abstract

The main purpose of this study was to investigate the relationship between the electron densities and Na/K ratio which has important role in breast cancer disease. Determinations of sodium and potassium concentrations in blood samples performed with inductive coupled plasma-atomic emission spectrometry. Electron density values of blood samples were determined via ZXCOM. Statistical analyses were performed for electron densities and Na/K ratio including Kolmogorov-Smirnov normality tests, Spearman's rank correlation test and Mann-Whitney U test. It was found that the electron densities significantly differ between control and breast cancer groups. In addition, statistically significant positive correlation was found between the electron density and Na/K ratios in breast cancer group.

Keywords: Blood samples; Breast cancer; Electron density; ICP-AES; Na/K ratio.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / blood*
  • Breast Neoplasms / pathology
  • Electrons
  • Female
  • Humans
  • Ions / blood
  • Minerals / blood*
  • Potassium / blood*
  • Sodium / blood*

Substances

  • Ions
  • Minerals
  • Sodium
  • Potassium