Gallbladder metastasis of renal clear cell carcinoma 15 years after primary cancer excision: a case report

J Med Case Rep. 2018 May 31;12(1):162. doi: 10.1186/s13256-018-1569-3.

Abstract

Background: Renal cell carcinoma is well-known for its propensity to metastasize to unusual sites. However, metastasis to the gallbladder has been rarely reported in the literature.

Case presentation: A 75-year-old Japanese (Asian) woman presented for further evaluation of a gallbladder polyp, 15 years after right radical nephrectomy for renal cell carcinoma. Computed tomography revealed a 12 mm enhancing pedunculated tumor in the gallbladder fundus. Open simple cholecystectomy was performed and the tumor was histologically confirmed as a metastasis of renal cell carcinoma to the gallbladder. Our patient is alive and has been disease-free for 3 years after cholecystectomy.

Conclusions: Although metastasis of renal cell carcinoma is a rare differential diagnosis of gallbladder tumors, simple cholecystectomy is likely to offer a chance of long-term survival for patients with gallbladder metastases of renal cell carcinoma.

Keywords: Gallbladder; Metastasis; Renal cell carcinoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma, Renal Cell / secondary*
  • Carcinoma, Renal Cell / surgery
  • Cholecystectomy
  • Female
  • Gallbladder Neoplasms / diagnostic imaging
  • Gallbladder Neoplasms / secondary*
  • Gallbladder Neoplasms / surgery
  • Humans
  • Kidney Neoplasms / pathology*
  • Kidney Neoplasms / surgery
  • Lung Neoplasms / secondary
  • Lung Neoplasms / surgery*
  • Nephrectomy