The Genetic Background of Neonatal Disease

Neonatology. 2018;113(4):400-405. doi: 10.1159/000487619. Epub 2018 May 31.

Abstract

More than 27,000 human genes have been sequenced and described. Only a few of these genes are relevant for common human diseases with regard to diagnostic or therapeutic purposes. This review describes the genetics of common traits and diseases with a particular focus on perspectives for drug discovery and drug therapy in neonates.

Keywords: Drug discovery; Genetics; Genome-wide association study; Neonate; Preterm infant; Risk factor; Trait.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Drug Discovery*
  • Genetic Background*
  • Genetic Predisposition to Disease
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / genetics*
  • Infant, Premature
  • Molecular Epidemiology
  • Risk Factors