Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors

Lai N Chan; Zhengshan Chen; Daniel Braas; Jae-Woong Lee; Gang Xiao; Huimin Geng; Kadriye Nehir Cosgun; Christian Hurtz; Seyedmehdi Shojaee; Valeria Cazzaniga; Hilde Schjerven; Thomas Ernst; Andreas Hochhaus; Steven M Kornblau; Marina Konopleva; Miles A Pufall; Giovanni Cazzaniga; Grace J Liu; Thomas A Milne; H Phillip Koeffler; Theodora S Ross; Isidro Sánchez-García; Arndt Borkhardt; Keith R Yamamoto; Ross A Dickins; Thomas G Graeber; Markus Müschen

doi:10.1038/s41586-018-0164-5

Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors

Nature. 2018 Jun;558(7711):E5. doi: 10.1038/s41586-018-0164-5.

Authors

Lai N Chan^{1

2}, Zhengshan Chen^{1

2}, Daniel Braas³, Jae-Woong Lee^{1

2}, Gang Xiao^{1

2}, Huimin Geng⁴, Kadriye Nehir Cosgun^{1

2}, Christian Hurtz⁴, Seyedmehdi Shojaee⁴, Valeria Cazzaniga⁴, Hilde Schjerven⁴, Thomas Ernst⁵, Andreas Hochhaus⁵, Steven M Kornblau⁶, Marina Konopleva⁶, Miles A Pufall⁷, Giovanni Cazzaniga⁸, Grace J Liu⁹, Thomas A Milne¹⁰, H Phillip Koeffler^{11

12}, Theodora S Ross¹³, Isidro Sánchez-García¹⁴, Arndt Borkhardt¹⁵, Keith R Yamamoto⁴, Ross A Dickins⁹, Thomas G Graeber³, Markus Müschen^{16

17}

Affiliations

¹ Department of Systems Biology, Beckman Research Institute and City of Hope National Medical Center, Pasadena, California, 91016, USA.
² City of Hope Comprehensive Cancer Center, Duarte, California, 91010, USA.
³ Department of Molecular and Medical Pharmacology, UCLA Metabolomics Center and Crump Institute for Molecular Imaging, University of California Los Angeles, Los Angeles, California, 90095, USA.
⁴ Departments of Laboratory Medicine and Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, 94143, USA.
⁵ Hämatologie/Onkologie, Klinik für Innere Medizin II, Universitätsklinikum Jena, 07743, Jena, Germany.
⁶ Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, 77030, USA.
⁷ Department of Biochemistry, University of Iowa, Iowa City, Iowa, 52242, USA.
⁸ Centro Ricerca Tettamanti, Clinica Pediatrica, Università di Milano-Bicocca, Ospedale S. Gerardo, 20052, Monza, MB, Italy.
⁹ Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, 3004, Australia.
¹⁰ MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK.
¹¹ Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.
¹² Division of Hematology/Oncology, Cedars-Sinai Medical Center, University of California School of Medicine, Los Angeles, California, 90095, USA.
¹³ Department of Internal Medicine and Cancer Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA.
¹⁴ Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca and Institute of Biomedical Research of Salamanca (IBSAL), 37007, Salamanca, Spain.
¹⁵ Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, 40225, Düsseldorf, Germany.
¹⁶ Department of Systems Biology, Beckman Research Institute and City of Hope National Medical Center, Pasadena, California, 91016, USA. mmuschen@coh.org.
¹⁷ City of Hope Comprehensive Cancer Center, Duarte, California, 91010, USA. mmuschen@coh.org.

PMID: 29849140
DOI: 10.1038/s41586-018-0164-5

Abstract

In Fig. 3c of this Letter, the the effects of CRISPR-Cas9-mediated deletion of NR3C1, TXNIP and CNR2 in patient-derived B-lineage leukaemia cells were shown. For curves depicting NR3C1 (left graph), data s for TXNIP (middle graph) were inadvertently plotted. This figure has been corrected online, and the original Fig. 3c is shown as Supplementary Information to this Amendment for transparency. The error does not affect the conclusions of the Letter. In addition, Source Data files have been added for the Figs. 1-4 and Extended Data Figs. 1-10 of the original Letter.

Publication types

Published Erratum

Grants and funding

R01 CA020535/CA/NCI NIH HHS/United States