Role of Lactobacillus in cervical cancer

Cancer Manag Res. 2018 May 16:10:1219-1229. doi: 10.2147/CMAR.S165228. eCollection 2018.

Abstract

Cervical cancer is a common malignant cancer among women worldwide. Changes in the vaginal microecological environment lead to multiple gynecological diseases, including cervical cancer. Recent research has shown that Lactobacillus may play an important role in the occurrence and development of cervical cancer. This review explores the role of Lactobacillus in cervical cancer. A total of 29 articles were included after identification and screening. The pertinent literature on Lactobacillus in cervical cancer from two perspectives, including clinical studies and experimental studies, was analyzed. An association network for the mechanism by which Lactobacillus induces cervical cancer was constructed. In addition, we provide direction and insight for further research on the role of Lactobacillus in cervical cancer.

Keywords: CIN; Lactobacillus; cervical cancer; microorganism.

Publication types

  • Review