Impact of polymorphisms in apoptosis-related genes on the outcome of childhood acute lymphoblastic leukaemia

Br J Haematol. 2019 Apr;185(1):159-162. doi: 10.1111/bjh.15415. Epub 2018 May 29.
No abstract available

Keywords: acute lymphoblastic leukaemia; apoptosis; chemotherapy; outcome; polymorphisms.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis / genetics*
  • Child
  • Dexamethasone / pharmacology
  • Genes, p53
  • Genotype
  • Glutathione Transferase / genetics
  • Humans
  • Jurkat Cells
  • Kaplan-Meier Estimate
  • Neoplasm Proteins / genetics
  • Precision Medicine
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Survival Rate
  • Treatment Outcome

Substances

  • Neoplasm Proteins
  • Dexamethasone
  • Glutathione Transferase
  • glutathione S-transferase M1