Prevalence of stromal corneal dystrophies in Lahore

J Pak Med Assoc. 2018 Apr;68(4):663-665.

Abstract

To determine the prevalence of Stromal Corneal Dystrophies (SCDs) in patient from Lahore hospitals. The study was performed between November, 2014 to July 2015 at the Layton Rahmatullah Benevolent Trust Hospital, Mughal Hospital, Mayo Hospital and General Hospital, Lahore. For the clinical evaluation of SCD by ophthalmologists examination of cornea was done by biomicroscopy, specular microscopy, topography, keratometry, orbscan and far visual acuity. Fifty cases of SCDs were recognized from Lahore, matching to hospital prevalence of 0.4%. The variables examined were age, gender, main complaint, corneal thickness, intraocular pressure and far visual acuity. SCDs are predominant in age group of 40-50 years. SCDs are more in male (n=30) as compared to females (n=20). Careful clinical evaluation, genotyping, governmental approval and subsequent development of human clinical trials of possible therapies and treatments should be taken to continue making improvement and effective control of SCDs.

Keywords: MSCD=Macular Stromal Corneal Dystrophy, LSCD=Lattice Stromal Corneal Dystrophy, CSCD=Congenital Stromal Corneal Dystrophy, SSCD=Schnyder Stromal Corneal Dystrophy, LRBT =Layton Rahmatullah benevolent Trust, CD=Corneal Dystrophy..

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Child
  • Child, Preschool
  • Corneal Dystrophies, Hereditary / epidemiology*
  • Corneal Dystrophies, Hereditary / physiopathology
  • Female
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Pakistan / epidemiology
  • Prevalence
  • Retrospective Studies
  • Sex Factors
  • Young Adult